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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專(zhuān)享價(jià)	數(shù)量
5 mg	In-stock	￥650.00	登錄后可見(jiàn)	- +
10 mg	In-stock	￥900.00	登錄后可見(jiàn)	- +
25 mg	In-stock	￥1600.00	登錄后可見(jiàn)	- +
50 mg	In-stock	￥2636.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專(zhuān)享價(jià)

數(shù)量

5 mg

In-stock

￥650.00

登錄后可見(jiàn)

- +

10 mg

In-stock

￥900.00

登錄后可見(jiàn)

- +

25 mg

In-stock

￥1600.00

登錄后可見(jiàn)

- +

50 mg

In-stock

￥2636.00

登錄后可見(jiàn)

- +

基本信息

英文名稱(chēng)	Y-27632 Dihydrochloride (Synonyms: Y-27632 2HCl ; trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride)
中文名稱(chēng)	trans-4-[(R)-1-氨基乙基]-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽 \| Y-27632 二鹽酸鹽 \| (R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽
CAS號(hào)	129830-38-2
分子式	C14H21N3O.2HCl
分子量	320.26 \| 247.34(free)
MDL	MFCD03490488
外觀	White to off-white powder
儲(chǔ)存條件	4°C, sealed storage, away from moisture

產(chǎn)品詳情

The ROCK family of Rho-associated serine-threonine protein kinases is known to play an important role in Rho-mediated cell adhesion and smooth muscle contraction. Y-27632 2HClis a potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM. One-hour treatment with 10 μMY-27632 2HCl blocks apoptosis of dissociated cultured human embryonic stem cells, increasing cloning efficiency by 25% and sustaining survival up to 30 passages.

相關(guān)文獻(xiàn)

A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats

https://doi.org/10.3390/toxins12050276

https://doi.org/10.1002/jcp.27910

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trans-4-[(R)-1-氨基乙基]-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽 | Y-27632 二鹽酸鹽 | (R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽

Y-27632 Dihydrochloride (Synonyms: Y-27632 2HCl ; trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride)

化學(xué)品安全說(shuō)明書(shū)(MSDS)

質(zhì)檢證書(shū)(COA)

小少妇bbbbbbbbbbbb,国产精品第一页,丁香花在线影院观看在线播放,扒开美女内裤狂揉下部

trans-4-[(R)-1-氨基乙基]-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽 | Y-27632 二鹽酸鹽 | (R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)環(huán)己烷甲酰胺 二鹽酸鹽

Y-27632 Dihydrochloride (Synonyms: Y-27632 2HCl ; trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride)

化學(xué)品安全說(shuō)明書(shū)(MSDS)

質(zhì)檢證書(shū)(COA)

trans-4-[(R)-1-氨基乙基]-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽 | Y-27632 二鹽酸鹽 | (R)-(+)-反式-4-(1-氨基乙基)-N-(4-吡啶基)環(huán)己烷甲酰胺二鹽酸鹽